ARTÍCULOS
Sevilla LM, Pons-Alonso O, Andrea Gallego, Mikel Azkargorta, Félix Elortza, and Pérez P 2024 Glucocorticoid receptor controls atopic dermatitis inflammation via functional interactions with P63 and autocrine signaling in epidermal keratinocytes. Cell Death & Dis. doi: https://www.nature.com/articles/s41419-024-06926-w
Deciphering the sex bias in housekeeping gene expression in adipose tissue: a comprehensive meta-analysis of transcriptomic studies.
Guaita-Cespedes M, Grillo-Risco R, Hidalgo MR, Fernández-Veledo S, Burks DJ, de la Iglesia-Vayá M, Galán A, Garcia-Garcia F.
Biol Sex Differ. 2023 Apr 18;14(1):20. https://pubmed.ncbi.nlm.nih.gov/37072826/
Fuertes-Agudo M, Luque-Tévar M, Cucarella C, Martín-Sanz P, Casado M. Advances in
Understanding the Role of NRF2 in Liver Pathophysiology and Its Relationship with Hepatic-Specific
Cyclooxygenase-2 Expression. Antioxidants (Basel). 2023 Jul 26;12(8):1491. PMID: 37627486 Free PMC article. Review. https://pubmed.ncbi.nlm.nih.gov/37627486/
Gallego A, Pérez P 2023 Loss of epidermal glucocorticoid receptor protects against whole body metabolic dysfunction upon chronic corticosterone treatment. Molecular Metabolism 74:101763 https://pubmed.ncbi.nlm.nih.gov/37364709/
Carceller-Zazo E, Sevilla LM, Pons-Alonso O, Chiner-Oms Á, Amazit L, An Vu T, Vitellius G, Viengchareun S, Comas I, Jaszczyszyn Y, Abella M, Alegre-Martí A, Estébanez-Perpiñá E, Lombès M, Pérez P. 2023 The mineralocorticoid receptor modulates timing and location of genomic binding by glucocorticoid receptor in response to synthetic glucocorticoids in keratinocytes. FASEB J. 37(1):e22709. https://pubmed.ncbi.nlm.nih.gov/36527388/
Rubio, T., Viana, R., Moreno-Estelles, M., Campos-Rodriguez, A., Sanz, P. “TNF and IL6/Jak2 signaling pathways are the main contributors of the glia-derived neuroinflammation present in Lafora disease, a fatal form of progressive myoclonus epilepsy” Neurobiol Dis 176: 105964 (2023). https://www.sciencedirect.com/science/article/pii/S0969996122003564?via%3Dihub
Roma-Mateo, C.*, Lorente-Pozo, S., Marquez-Thibaut, L., Moreno-Estelles, M., Garces, C., Gonzalez, D., Lahuerta, M., Aguado, C., Garcia-Gimenez, J.L., Sanz, P.*, Pallardó, F.V. (*Co-corresponding authors). “Age-related microRNA overexpression in Lafora disease male mice provides links between neuroinflammation and oxidative stress” Int. J. Mol. Sci 24, 1089 (2023).
https://www.mdpi.com/1422-0067/24/2/1089
Kumarasinghe, L., Garcia-Gimeno, M.A., Ramirez, J.M., Mayor, U., Zugaza, J.L., Sanz, P. “P-Rex1 is a novel substrate of the E3 ubiquitin ligase Malin associated with Lafora disease”. Neurobiol. Dis 177: 105998 (2023).
https://www.sciencedirect.com/science/article/pii/S0969996123000128?via%3Dihub
Moreno-Estellés, M., Campos-Rodriguez, A., Rubio-Villena, C., Kumarasinghe, L., Garcia-Gimeno, M.A., Sanz, P. “Deciphering the polyglucosan accumulation present in Lafora disease by using an astrocytic cellular model”. Int. J. Mol. Sci. 24, 6020 (2023).
https://www.mdpi.com/1422-0067/24/7/6020
Calatayud-Baselga, I., Casares-Crespo, L., Franch-Ibañez, C., Guijarro-Nuez, J., Sanz, P. and Mira H. “Autophagy drives the conversion of developmental neural stem cells to the adult quiescent state”. Nature Commun. 14, 7541 (2023).
https://www.nature.com/articles/s41467-023-43222-1
Rubio, T., Campos-Rodriguez, A. and Sanz, P. “Beneficial effects of fingolimod in a Lafora disease mouse model by preventing reactive astrogliosis-derived neuroinflammation and brain infiltration of T-lymphocytes”. Mol. Neurobiol. PMID: 37971656 (2023). https://link.springer.com/article/10.1007/s12035-023-03766-1
CAPÍTULOS DE LIBRO
Serratosa, J.M., Burgos, D.F., Zafra-Puerta, L., Iglesis-Cabeza, N., Sanz, P. and Sanchez, M.P. “Progessive myoclonus epilepsy of Lafora. Treatment with Metformin”. In Noebels/Jasper’s Basic Mechanisms of Epilepsies, 5th Edition, Chapter 54, pg.1125-1139 (2023).
COMUNICACIONES A CONGRESOS
Paloma Pérez. MR-GR crosstalk in the skin. ESAC ADMIRE joint symposium Freiburg 19 y 20 de marzo 2024. Comunicación oral invitada
Andrea Alegre-Martí, Alba Jimenez-Panizo, Agustina Lafuente, Montserrat Abella, Thomas A Johnson, Paloma Pérez, Juan Fernández-Recio, Diego M. Presman, Gordon L. Hager, Pablo Fuentes-Prior, Eva Estébanez-Perpiñá. Structural basis for glucocorticoid receptor multimerization. ENDO meeting Bostol, abril 2024. Comunicación oral
Andrea Gallego and Paloma Pérez. Skin glucocorticoid signaling improves whole body metabolism. 46 congreso SEBBM A Coruña 4 de setiembre 2024. Comunicación oral invitada
Sanz, P. “Glial alterations in the glutamatergic and GABAergic signaling pathways in a mouse model of Lafora disease” Invited presentation at the Ninth Lafora Workshop. San Diego (USA). September 2024.
Marta Casado 2024. Beneficial effects of hepatic cyclooxygenase-2 expression against NAFLD/NASH: A potential therapeutic target. Invitación en el Symposium Gastroenterology del XXVI Congreso de la Sociedad Argentina de Fisiología (SAFIS) y la Asociación Latinoamericana de Ciencias Fisiológicas (ALACF) 19-22 de noviembre de 2024 Buenos Aires, Argentina.
Paloma Pérez. 2023 Skin glucocorticoid signaling impacts the whole-body metabolism.
Nuclear Receptors and Metabolism. The MetNet-NuRCaMeIn-French Liaison.
1st Spanish-French Nuclear Receptors Joint Meeting 9th Annual MetNet International Meeting
Barcelona, October 10-11, 2023
Sanz, P. “Neuroinflammation and LD: facts and therapeutic opportunities”. Invited presentation at the Eight International Lafora disease Workshop. Bolonia, Italy. October 2023.