The Challenge of Tuberculosis in the 21st Century (ERS Monograph). Con la colaboración de Iñaki Comas y su grupo de investigación

Capítulo accesible en el repositorio Digital.CSIC:

Recent improvements in WGS are transforming how we use genomics for TB epidemiology and diagnosis. The increased precision of new techniques allows us to identify transmission with unprecedented resolution and design tailored strategies to reduce the incidence of TB at a local and global scale. In addition, compared with limited commercial molecular tests, diagnosis of drug resistance using the complete genome can interrogate all drug-resistance targets through the use of catalogues of resistance-associated variants, including a catalogue sponsored by the WHO. All these advances are making their way into the clinical setting and will eventually allow us to slow the spread of TB and offer personalised care to all patients.

http://hdl.handle.net/10261/334481